[{"data":1,"prerenderedAt":210},["ShallowReactive",2],{"ingredient-sodium-metabisulfite":3},{"id":4,"title":5,"body":6,"category":27,"commonProducts":167,"description":171,"extension":172,"icon":173,"inciName":5,"irritantReason":174,"isCommonIrritant":175,"keyFacts":176,"localNames":186,"meta":187,"navigation":188,"path":189,"relatedArticles":190,"seo":197,"severity":198,"slug":199,"stem":200,"subtitle":201,"symptoms":202,"synonyms":207,"__hash__":209},"ingredients/learn/ingredients/sodium-metabisulfite.md","Sodium Metabisulfite",{"type":7,"value":8,"toc":157},"minimark",[9,14,29,32,36,39,42,64,68,94,98,117,120,124,127,131],[10,11,13],"h2",{"id":12},"what-is-sodium-metabisulfite","What is Sodium Metabisulfite?",[15,16,17,20,21,24,25,28],"p",{},[18,19,5],"strong",{}," (INCI: Sodium Metabisulfite; chemical names: Sodium Pyrosulfite, Disodium Disulfite; food additive code: E223) is an inorganic salt belonging to the sulfite family. It functions as an ",[18,22,23],{},"antioxidant"," and ",[18,26,27],{},"preservative",", preventing oxidative degradation of products — particularly important in formulations containing vitamins (like ascorbic acid/vitamin C) that are prone to oxidation. It is commonly used in food preservation (wine, dried fruits, seafood), water treatment, and pharmaceutical preparations, and appears in some skincare products.",[15,30,31],{},"In cosmetics, sodium metabisulfite is less common than organic preservatives but appears in some dermatological creams, whitening preparations, and vitamin C products where it helps stabilize the formula against discoloration and potency loss. It can generate sulfur dioxide in aqueous solution, which contributes to its antimicrobial and antioxidant effects.",[10,33,35],{"id":34},"why-does-sodium-metabisulfite-cause-reactions","Why does Sodium Metabisulfite cause reactions?",[15,37,38],{},"Sodium metabisulfite causes reactions through immune-mediated mechanisms in sulfite-sensitive individuals. The sulfite class of compounds is a known contact allergen group, and sodium metabisulfite is included in standard ACDS patch test panels to screen for this sensitivity.",[15,40,41],{},"Key considerations:",[43,44,45,52,58],"ul",{},[46,47,48,51],"li",{},[18,49,50],{},"Contact dermatitis",": Topical exposure to sodium metabisulfite can trigger allergic contact dermatitis in sensitized individuals — redness, pruritus, and dermatitis at the application site",[46,53,54,57],{},[18,55,56],{},"Cross-reactivity within sulfites",": Sensitivity to sodium metabisulfite typically predicts cross-reactivity with other sulfites including sodium bisulfite, potassium metabisulfite, and sulfur dioxide",[46,59,60,63],{},[18,61,62],{},"Food sulfite vs. topical sulfite sensitivity",": Sulfite sensitivity is best known in the context of food allergies (reactions to wine, preserved foods), but topical sensitization is a separate phenomenon. Some individuals are sensitive via both routes; others only one",[10,65,67],{"id":66},"where-is-sodium-metabisulfite-found-in-products","Where is Sodium Metabisulfite found in products?",[43,69,70,76,82,88],{},[46,71,72,75],{},[18,73,74],{},"Vitamin C skincare preparations",": As a preservative/antioxidant stabilizer",[46,77,78,81],{},[18,79,80],{},"Skin lightening products",": In some formulations containing easily-oxidized active ingredients",[46,83,84,87],{},[18,85,86],{},"Pharmaceutical topicals",": As a reducing agent or preservative in some medicated creams",[46,89,90,93],{},[18,91,92],{},"Hair processing chemicals",": In some professional salon products",[10,95,97],{"id":96},"how-to-spot-sodium-metabisulfite-on-labels","How to spot Sodium Metabisulfite on labels",[43,99,100,105,111],{},[46,101,102,104],{},[18,103,5],{}," — INCI name",[46,106,107,110],{},[18,108,109],{},"Sodium Pyrosulfite"," — alternate chemical name",[46,112,113,116],{},[18,114,115],{},"E223"," — food code (not used on cosmetic labels)",[15,118,119],{},"Also watch for related sulfites: Sodium Bisulfite, Potassium Metabisulfite, Sodium Sulfite.",[10,121,123],{"id":122},"in-indian-products","In Indian products 🇮🇳",[15,125,126],{},"Sodium metabisulfite is more commonly encountered in pharmaceutical preparations in India than in standard cosmetics. Some whitening or brightening creams containing vitamin C derivatives may use it as a stabilizing antioxidant. It is also present in professional salon bleaching and coloring formulations. Indian consumers with known sulfite food sensitivity should check topical products for this ingredient.",[10,128,130],{"id":129},"safer-alternatives","Safer alternatives",[43,132,133,139,145,151],{},[46,134,135,138],{},[18,136,137],{},"Ascorbic acid itself as antioxidant",": When used at appropriate concentrations and pH, ascorbic acid can protect formulas without the sulfite concern",[46,140,141,144],{},[18,142,143],{},"Tocopherol (Vitamin E)",": A natural oil-phase antioxidant that is well-tolerated",[46,146,147,150],{},[18,148,149],{},"Ferulic acid",": Synergistic antioxidant with ascorbic acid; no sulfite concerns",[46,152,153,156],{},[18,154,155],{},"BHT (Butylhydroxytoluene)",": Synthetic antioxidant with different allergy profile — useful alternative for sulfite-sensitive individuals",{"title":158,"searchDepth":159,"depth":159,"links":160},"",2,[161,162,163,164,165,166],{"id":12,"depth":159,"text":13},{"id":34,"depth":159,"text":35},{"id":66,"depth":159,"text":67},{"id":96,"depth":159,"text":97},{"id":122,"depth":159,"text":123},{"id":129,"depth":159,"text":130},[168,169,170],"Some skincare products","Food preservative","Pharmaceutical preparations","An antioxidant and preservative used in some skincare products. Can cause allergic or irritant reactions in individuals with sulfite sensitivity, particularly those who also react to sulfites in foods.","md","🧪",null,false,[177,180,183],{"label":178,"value":179},"Sulfite class","Belongs to the sulfite/bisulfite family of antioxidants; shares allergy risk with sodium bisulfite, potassium metabisulfite, and sulfur dioxide",{"label":181,"value":182},"Cross-reactivity with food","Food sulfite sensitivity (reactions to wine, dried fruit, preserved foods) does not necessarily predict topical skin sensitivity, but the overlap exists",{"label":184,"value":185},"ACDS listing","Included in ACDS patch test series as an antioxidant/preservative allergen",[],{},true,"/learn/ingredients/sodium-metabisulfite",[191,194],{"slug":192,"title":193},"/learn/reading-cosmetic-labels","How to Read Cosmetic Labels",{"slug":195,"title":196},"/learn/food-allergens-in-skincare","Food Allergens in Skincare",{"title":5,"description":171},"low","sodium-metabisulfite","learn/ingredients/sodium-metabisulfite","An antioxidant preservative that can trigger reactions in sulfite-sensitive individuals",[203,204,205,206],"Contact dermatitis in sulfite-sensitive individuals","Urticaria (hives) in sulfite-allergic individuals","Redness and stinging at application site","Possible respiratory symptoms in severe sulfite allergy",[109,208,115],"Disodium disulfite","JiAxNAvAHyCwx2Z_fv2Bdzr7h1TVlGvUhYVp-Pqnmtk",1778416676213]