Allergen & irritant analysis
This facial treatment from Paula's Choice lists 25 ingredients. AllerNote's analysis found no commonly-flagged contact allergens or irritants in the INCI list — though no formula is universally safe. No added fragrance, parabens, MI / MCI (isothiazolinones), formaldehyde-releasing preservatives, SLS / SLES sulfates were detected in the listed ingredients.
No commonly-flagged contact allergens or irritants were detected in the listed ingredients — though no formula is universally safe.
Not detected: added fragrance, parabens, MI / MCI (isothiazolinones), formaldehyde-releasing preservatives, SLS / SLES sulfates.
Generated from this product's ingredient list and AllerNote's allergen database — educational, not medical advice or a substitute for patch testing.
Benefits
Key Ingredients
- 1AntioxidantsShields skin from free radical damage.
- 2Vitamin CBrightens, evens tone, and supports collagen.
- 3NiacinamideStrengthens, smooths, and brightens skin.
- 4ExfoliatorsRemoves dead skin cells to smoothe texture.
Full Ingredient List
25INCI (full list, INCI order): water, niacinamide, pentylene glycol, butylene glycol, glycerin, acetyl glucosamine, ascorbyl glucoside, glycyrrhiza glabra root extract, spiraea ulmaria extract, portulaca oleracea extract, camellia japonica flower extract, epigallocatechin gallate, boerhavia diffusa root extract, camellia sinensis leaf extract, allantoin, lecithin, pullulan, panthenol, silica, xanthan gum, sclerotium gum, propanediol, sodium phytate, phenoxyethanol, ethylhexylglycerin
Tap any ingredient to see details
Potential Concerns
- May Worsen EczemaMay worsen itching or irritation for eczema.
- May Worsen RosaceaCan trigger flare-ups in rosacea-prone skin.
Frequently asked questions
Is Clinical Niacinamide 20% Treatment fragrance-free?
No added fragrance or EU-labelled fragrance allergens were detected in Clinical Niacinamide 20% Treatment's listed ingredients. "Not detected" isn't an absolute guarantee, but it's a good sign for fragrance-sensitive skin — confirm against the current pack and your own triggers.
Is Clinical Niacinamide 20% Treatment paraben-free?
No parabens were detected in Clinical Niacinamide 20% Treatment's listed ingredients. Worth keeping in perspective: parabens are among the least common cosmetic allergens, so "paraben-free" matters far less for reactive skin than avoiding fragrance or the preservative MI/MCI.
Is Clinical Niacinamide 20% Treatment suitable for sensitive or allergy-prone skin?
No commonly-flagged allergens or irritants were detected in Clinical Niacinamide 20% Treatment, which is encouraging for reactive skin — but "no known flags" isn't the same as "safe for everyone." Patch test before full use, and check it against your own allergen profile on AllerNote.

