Balsam of Peru
A natural fragrance resin and classic "marker" allergen — a positive patch test points to broad fragrance sensitivity and a long list of cross-reactors
INCIMyroxylon Pereirae
- Category
- Fragrance
- Risk level
- medium
- What it is
- A natural resin from the Myroxylon balsamum tree, rich in cinnamates, benzoates, and vanillin
- Why it matters
- A "marker" allergen — a positive patch test predicts broader fragrance sensitivity
- Cross-reactors
- Cinnamon, vanilla, citrus peel, cloves, balsam of Tolu, and many synthetic fragrances
- Patch testing
- On the baseline series alongside fragrance mix I and II
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This ingredient may appear under any of these names:
Commonly found in
Possible reactions
- Redness or rash where scented products are applied
- Cheilitis — sore, scaling lips from lip products or toothpaste
- Hand dermatitis from creams
- Eczema flare in fragrance-exposed areas
- Flares that some people link to eating its cross-reacting foods
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What is balsam of Peru?
Balsam of Peru (INCI: Myroxylon Pereirae) is a natural resin tapped from the bark of the Myroxylon balsamum tree of Central America. It has a warm, vanilla-and-cinnamon scent and has been used for centuries in perfumery, flavouring, and topical medicine. Chemically it's a complex brew of cinnamates, benzoates, vanillin, and related aromatic compounds — which is precisely why it's both useful as a fragrance and important as an allergen.
In cosmetics it appears in perfumes, lip products, hand and body creams, and flavoured toothpastes, and historically in wound-healing ointments. Despite being "natural," it's one of the most clinically significant fragrance allergens.
Why it's a "marker" allergen
The most important thing about balsam of Peru isn't balsam of Peru itself — it's what a reaction to it tells you. Because it contains so many of the same aromatic chemicals found throughout natural and synthetic fragrances, dermatologists use it on the baseline patch-test series as a marker for fragrance allergy. A positive result suggests you're likely to react to fragrance broadly, and should approach scented products with caution rather than chasing one specific chemical.
That's also why it travels with a long list of cross-reactors. People who react to balsam of Peru often react to:
- Cinnamon and cinnamon oil
- Vanilla and vanillin
- Citrus peel oils
- Cloves and other warm spices
- Balsam of Tolu (a close relative)
- Many synthetic fragrances that recreate these notes
The diet question (handle with care)
A genuinely useful but often-misapplied fact: a subset of people with balsam-of-Peru allergy and stubborn, widespread dermatitis improve on a low-balsam diet — temporarily cutting back on foods rich in the same chemicals (cinnamon, vanilla, citrus, cloves, tomatoes, certain spices). This is systemic contact dermatitis.
But this matters for a minority, not everyone with a positive test, and it should be a short, dermatologist-guided trial, not a permanent self-imposed restriction. Most people manage balsam-of-Peru allergy purely by avoiding fragranced topical products.
If your patch-test report lists balsam of Peru, read it as "you're probably fragrance-allergic," and let that guide your whole routine — fragrance-free skincare, haircare, and lip care — rather than only scanning for the words "Myroxylon pereirae."
Where it shows up
- Lip products and lipstick — a frequent cause of cheilitis (sore, scaling lips)
- Flavoured toothpaste — cinnamon/spice flavours especially
- Perfume and scented creams — perfume, hand cream, body lotion
- Topical ointments — older healing/wound preparations sometimes contained it
How to spot and avoid it
- Read labels for Myroxylon Pereirae, Balsam of Peru, Peru Balsam, or Peruvian Balsam.
- Go fragrance-free generally — because it's a marker, avoiding all fragrance is usually more effective than chasing this one name.
- Swap lip products and toothpaste for plain, flavour-free options if you get recurrent sore lips.
- Check "natural" and "botanical" products, which often lean on balsams and essential oils.
When to see a dermatologist
Persistent lip, hand, or facial dermatitis, or eczema that flares with perfumed products, is worth patch testing. Balsam of Peru sits on the baseline series with fragrance mix I and II, so a dermatologist can confirm fragrance sensitivity and — if your dermatitis is severe and widespread — discuss whether a short low-balsam diet trial is worth it.
The bottom line
Balsam of Peru is a natural fragrance resin whose real value is diagnostic: react to it, and you've likely learned you're fragrance-allergic across the board. Treat a positive result as a cue to go broadly fragrance-free, watch your lip products and toothpaste, and reserve the diet angle for stubborn cases under medical guidance.
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References & further reading
- Balsam of Peru (Myroxylon pereirae) allergy — overview DermNet
- Fragrance and balsam of Peru contact allergy — clinical review PubMed / Contact Dermatitis
- CosIng — Myroxylon pereirae entry European Commission
