Allergen & irritant analysis
2 flaggedThis serum from Avène lists 25 ingredients. AllerNote's analysis flags 1 known contact allergen and 1 common irritant in the INCI list. That includes 1 EU-labelled fragrance allergen (parfum). No parabens, MI / MCI (isothiazolinones), formaldehyde-releasing preservatives, SLS / SLES sulfates were detected in the listed ingredients.
- ParfumKnown allergen (fragrance): Fragrance Mix I
- Sodium hydroxideStrong alkaline substance that can be highly corrosive and irritating in high concentrations; used safely in cosmetics only in neutralized, low concentrations for pH adjustment.
Not detected: parabens, MI / MCI (isothiazolinones), formaldehyde-releasing preservatives, SLS / SLES sulfates. Contains: added fragrance.
Based on what's flagged, take extra care if you're among:
- People with fragrance allergy or fragrance-sensitive skin
Generated from this product's ingredient list and AllerNote's allergen database — educational, not medical advice or a substitute for patch testing.
Benefits
Key Ingredients
- 1AntioxidantsShields skin from free radical damage.
- 2Vitamin CBrightens, evens tone, and supports collagen.
- 3Vitamin EProtects skin and soothes irritation.
- 4Hyaluronic AcidHydrates by attracting and holding water.
Full Ingredient List
25INCI (full list, INCI order): water, glycerin, isododecane, pentylene glycol, dimethicone, ascorbyl glucoside, polymethyl methacrylate, tocopheryl glucoside, artemia extract, c12-20 alkyl glucoside, c14-22 alcohols, caprylic/capric triglyceride, cetrimonium bromide, citric acid, disodium edta, parfum, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, polysorbate 60, sodium benzoate, sodium citrate, sodium hyaluronate, sodium hydroxide, sorbitan isostearate, tocopherol, xanthan gum
Tap any ingredient to see details
Potential Concerns
- May Worsen RosaceaCan trigger flare-ups in rosacea-prone skin.
- May Worsen EczemaMay worsen itching or irritation for eczema.
Frequently asked questions
Does A-Oxitive Antioxidant Defense Serum contain fragrance allergens?
Yes — analysing the INCI list, AllerNote found 1 of the EU-labelled fragrance allergens: parfum. If you're fragrance-sensitive or patch-test positive to a fragrance mix, treat A-Oxitive Antioxidant Defense Serum with caution and patch test before full use.
Is A-Oxitive Antioxidant Defense Serum paraben-free?
No parabens were detected in A-Oxitive Antioxidant Defense Serum's listed ingredients. Worth keeping in perspective: parabens are among the least common cosmetic allergens, so "paraben-free" matters far less for reactive skin than avoiding fragrance or the preservative MI/MCI.
Is A-Oxitive Antioxidant Defense Serum suitable for sensitive or allergy-prone skin?
It depends on your specific triggers. A-Oxitive Antioxidant Defense Serum contains 1 flagged allergen and 1 irritant (listed in the analysis above). If none are on your personal allergen list it may suit you, but patch test first — add your allergens to AllerNote to check A-Oxitive Antioxidant Defense Serum against your own profile.

