Allergen & irritant analysis
2 flaggedThis serum from Neutrogena lists 16 ingredients. AllerNote's analysis flags 1 known contact allergen and 1 common irritant in the INCI list. No added fragrance, parabens, MI / MCI (isothiazolinones), formaldehyde-releasing preservatives, SLS / SLES sulfates were detected in the listed ingredients.
- Propylene glycolKnown allergen (solvent): Propylene Glycol
- Sodium hydroxideStrong alkaline substance that can be highly corrosive and irritating in high concentrations; used safely in cosmetics only in neutralized, low concentrations for pH adjustment.
Not detected: added fragrance, parabens, MI / MCI (isothiazolinones), formaldehyde-releasing preservatives, SLS / SLES sulfates.
Generated from this product's ingredient list and AllerNote's allergen database — educational, not medical advice or a substitute for patch testing.
Benefits
Key Ingredients
- 1AHAExfoliates skin for a brighter complexion.
- 2BHAUnclogs pores and reduces excess oil.
- 3PHAGently exfoliates and hydrates with less irritation.
- 4ExfoliatorsRemoves dead skin cells to smoothe texture.
Full Ingredient List
16INCI (full list, INCI order): water, propylene glycol, glycolic acid, dimethicone, sodium hydroxide, mandelic acid, gluconolactone, neopentyl glycol diheptanoate, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, salicylic acid, t-butyl alcohol, dimethicone crosspolymer, polyacrylate crosspolymer-6, polysorbate 60, sorbitan isostearate, disodium edta
Tap any ingredient to see details
Potential Concerns
- May Worsen RosaceaCan trigger flare-ups in rosacea-prone skin.
- May Worsen DrynessCan strip moisture and worsen dryness.
- May Worsen EczemaMay worsen itching or irritation for eczema.
Frequently asked questions
Is Clear & Defend+ Daily Serum fragrance-free?
No added fragrance or EU-labelled fragrance allergens were detected in Clear & Defend+ Daily Serum's listed ingredients. "Not detected" isn't an absolute guarantee, but it's a good sign for fragrance-sensitive skin — confirm against the current pack and your own triggers.
Is Clear & Defend+ Daily Serum paraben-free?
No parabens were detected in Clear & Defend+ Daily Serum's listed ingredients. Worth keeping in perspective: parabens are among the least common cosmetic allergens, so "paraben-free" matters far less for reactive skin than avoiding fragrance or the preservative MI/MCI.
Is Clear & Defend+ Daily Serum suitable for sensitive or allergy-prone skin?
It depends on your specific triggers. Clear & Defend+ Daily Serum contains 1 flagged allergen and 1 irritant (listed in the analysis above). If none are on your personal allergen list it may suit you, but patch test first — add your allergens to AllerNote to check Clear & Defend+ Daily Serum against your own profile.

